Lifestyle, Nootropics, Supplements

13 best Nootropics, supplements and amino acids worth taking before and after Drinking

   Biohacking is a lifestyle that is usually focused on living healthy, improving the quality of life , increasing brain capacity and productivity, as well as focusing on the body. But once in a while , many people like to unwind, and just have a fun with a bunch of friends. Sometimes it involves drinking and that usually ends up with a bad hangover. There are some steps to make , and some nootropics and supplements to take if you want to reduce the intensity of hangover the day after drinking, and maybe even stay productive.



Glycine is a non-essential amino acid and also a neurotransmitter in our brains. In relation to alcohol

drinking, Glycine can protect the liver from intoxication by alcohol, because it has antioxidant propertis. It also reduces the concentrations of Alcohol in the blood by stimulating the metabolism of Alcohol in the stomach.

 N Acetyl Cysteine

N Acetyl Cysteine is a acetylated version of amino acid L Cysteine. Acetyl L Cysteine is proven to increase levels of Glutathione , which is the most powerful antioxidant in the human body. N-acetyl Cysteine targets glutamate receptors and restore glutamate homeostasis. You can consume 200- 1000 miligrams of Acetyl-L-Cysteine at least 30 minutes before drinking as a prevention against next morning hangover. Anecdotal evidence is , that N-Acetyl Cysteine is like a miracle when it comes to preventing hangovers- some people claim that it fully eliminates a hangover after drinking even 10 -11 shots during night.

Alpha Lipoic Acid

Alpha Lipoic Acid is an amino acid that is another powerful antioxidant. It contributes to the glutathione production. It eliminates free radicals, and helps the liver detox.



L theanine   

L theanine is an amino acid extracted from green tea. L theanine can be beneficial before and after drinking

as  well. Based on a study, when given to mice, L –theanine was able to lower blood levels of alcohol. It serves as a prevention against a bad impact of acetaldehyde. This substance is created in the liver by conversion from Alcohol. But be careful! If you are a drinker that drinks excessively, L –theanine before drinking can lower your alcohol tolerance – you can get drunk faster.

B vitamins

One of the Alcohol effects is , that it flushes out B vitamins from the body. Taking a B complex befre or after drinking Alcohol can be a good idea. Specifically, vitamins B1, B2, B3 (niacin), Panthotenic acid and vitamin B12.

Activated Charcoal

 Activated Charcoal is a black powder that can stop toxins from absorbing. Activated charcoal is a substance that is helpful against alcohol intoxication, but not very practical. You have to use it fast after alcohol consumption. Consuming activated charcoal before drinking is tricky- charcoal will absorb the Alcohol before it will get to the stomach, but you would not feel effect of alcohol as well- that means no buzz and no euphoria. If your plan is to go to a company teambuilding  and have a couple of drinks but stay completely sober, consuming some activated charcoal before the event is the way to go.


Liposomal Glutathione

Glutathione is the strongest antioxidant in the human body. Liposomal glutathione is a good choice to raise glutathione levels. Based on a study, oral supplementation with Glutathione can raise body glutathione levels by 40 percent. In conjuction with alcohol consumption, liposomal glutathione is also reducing acetaldehyde toxicity in the body.


Milk Thistle

Milk Thistle is a plant that has been used in bodybuilding world for years, mostly because of its liver protection. Milk Thisle offers more benefits than that, such as reduction of cholesterol levels, improving insulin sensitivity, and increased resistance to oxidative stress. You can consume milk thistle before as well as after the consumption of alcohol for liver protection purposes.

Green Tea extract

Green tea is a very potent antioxidant. It contains catechins , that help prevent cell damage, help with fat oxidation, improve blood flow and insulin sensitivity. So we recommend to drink a cup of green tea before the party and also a cup the next day. You will get a dose of epicatechins, flavonoids , a small dose of caffeine and L-theanine which will all be beneficial to your mood and well-being.



Turmeric is a spice that offers a lot of health benefits, such as heart disease prevention, increasing BDNF factor, preventing Alzheimer’s disease and theoretically even preventing Cancer. Tumeric is also good for reducing negative side effects of hangover. It lowers inflammation and oxidative stress, and prevents liver toxicity induced by alcohol consumption. To increase bioavailability by 2000 percent, you should add bioperine.



Dihydromyricetin is a type of flavonoid , that prevents hangover by enhancing enzymes in the liver responsible for breaking down alcohol and block alcohol from reaching GABA receptors in the brain that are responsible for feeling of intoxication. We recommend taking Dihydromyricetin as soon as possible after your last drink- or after coming home from party- in this case,you already enjoyed the effects of alcohol on Gaba receptors and you want your body to get rid of all the toxins.


Rhodiola Rosea

   Rhodiola Rosea is an adaptogen and a strong antioxidant. Rhodiola Rosea can help you with eliminating fatique after night out. Rhodiola is helping to sustain certain brain chemicals, sucha s dopamine, serotonin and norepinephrine. You brain is lacking certain chemicals after drinking night because it lacks sleep and the body is combating with eliminating alcohol. Rhodiola can alo help with eliminating hangover depression.


   Magnesium is a key mineral for a lot of processes in the body. And this very important mineral is being depleted by alcohol consumption. Alcohol acts as a Magnesium diuretic .


Heavy drinking is bad . But taking couple of drinks can enhance your social life and is very enjoyable. What is the worst thing about drinking – at least for most people- is the loss of control and nasty hangover the next day. But with good combination of supplements, you can easily lower the impact of alcohol on your body by 30 -40 percent! Just take some Glycine, Acetyl-l- Cysteine and Acetyl-l-carnitine before drinking , take some strong and high quality form of magnesium before sleep ( like Magnesium Threonate) , and for calming down but also slight energy boost you can take some rhodiola rosea. With these techniques, the hangovers will be “over” and yes, you will be able to enjoy drinking once in a while 🙂


DISCLAIMER: The information included in this article is intended for entertainment and informational purposes only. It is not intended nor implied to be a substitute for professional medical advice. Prior to buying anything, check that it is compliant where you live with your current government laws.


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